Product Details
Semax — Nootropic Neuropeptide (ACTH 4-10 Analog)
Semax is a synthetic heptapeptide derived from the ACTH (adrenocorticotropic hormone) fragment 4-10, with the addition of a Pro-Gly-Pro C-terminal tripeptide sequence that enhances metabolic stability and CNS penetration. Originally developed at the Institute of Molecular Genetics in Russia, Semax is one of the most well-characterized nootropic peptides in neuroscience research.
Mechanism of Action
Semax increases brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) expression in the hippocampus and cortex. It modulates serotonergic and dopaminergic neurotransmission, enhances acetylcholine release, and activates MAPK/ERK signaling cascades involved in synaptic plasticity and long-term potentiation. Notably, Semax achieves its nootropic effects without the adrenocortical stimulation typical of ACTH-related peptides.
Research Applications
- BDNF and NGF expression modulation studies
- Cognitive function and memory formation research
- Neuroplasticity and synaptic remodeling
- Neuroprotection in ischemic injury models
- Neurotransmitter system modulation (dopamine, serotonin)
Product Specifications
- Quantity: 10mg per vial
- Purity: ≥99% (HPLC verified)
- Form: Lyophilized powder
- Storage: Refrigerate after reconstitution
- Testing: USA lab tested, COA available
For research purposes only. Not for human use or consumption.
Stacey Brady verified owner
Fast delivery and product arrived in perfect shape.
Anonymous verified owner
Fast shipping, great quality.
Kyle verified owner
Good stuff.
Blaine Randolph verified owner
Great stuff.
Angel verified owner
Excellent experience from order to delivery.
Alex Spitler verified owner
Great product.
Bryan W. verified owner
Works like it should, with careful packaging.
Robert L. verified owner
My one stop shop for research compounds.